Denver Broncos (+4) at Buffalo Bills (O/U 38)
No confidence in Denver. None. None. None. Buffalo at home should cover like a blanket.
Pick: Buffalo Bills -4
Carolina Panthers (+10) at New Orleans Saints (O/U 47)
This has the makings of a shootout. The Saints offense can score from anywhere on the field. Will the Panthers hold up their end of the bargain? We sure hope so.
Pick: Over 47
Dallas Cowboys (+6.5) at New England (O/U 46)
This has New England written all over it. Their defense has been lights out but the Cowboys will be able to run the ball enough to make this a one score outcome.
Pick: Dallas Cowboys +6.5
Green Bay Packers (+3) at San Francisco 49ers (O/U 48)
How big is this for both teams? The Packers have a half game lead in the NFC North while the 49ers have a full game lead in the NFC West. The Packers are coming off a bye week. Two weeks to prepare with Aaron Rodgers as your quarterback is worth taking the field goal.
Pick: Green Bay Packers +3